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Isomorphic Labs raises over £450m in Series A funding led by Thrive Capital to scale AI drug design and clinical programmes

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Isomorphic Labs
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Demis Hassabis
💰
£450m
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London, United Kingdom
Mar 31, 2025

Isomorphic Labs, an AI-first drug design and development company, today announced it has raised over £450 million in its first external funding round. The financing round is led by Thrive Capital, with participation from GV, and follow-on capital from existing investor, Alphabet.

Isomorphic Labs was founded with the ambition to leverage the power of AI to reimagine and accelerate drug discovery to bring much-needed treatments to millions of patients globally. The company aims to apply its pioneering AI drug design engine to deliver biomedical breakthroughs and is advancing drug design programs across multiple therapeutic areas and drug modalities.

Since its founding, the company has developed a number of next-generation AI models that come together to form its unified AI drug design engine that works across multiple therapeutic areas and drug modalities. One example breakthrough model is AlphaFold 3, developed and released in May 2024 by Isomorphic Labs together with Google DeepMind, with the ability to accurately predict the structure and interactions of all of lifeʼs molecules. Leveraging these state-of-the-art AI technologies, Isomorphic Labs has established a drug discovery portfolio consisting of partnered programs with pharmaceutical industry leaders Eli Lilly and Novartis, as well as internal programs primarily focused in oncology and immunology. Novartis and Isomorphic Labs recently expanded the scope of their original collaboration just over a year after initiating the relationship.

The investment will accelerate Isomorphic Labsʼ frontier AI research and development, to rapidly advance the companyʼs next-generation AI drug design engine. Isomorphic Labs will consequently be expanding its team of world-class talent as part of its next phase of growth.

We're excited to bring together a top-tier investor group with deep AI and life sciences expertise as we aim to transform this industry through an interdisciplinary approach. This funding will further turbocharge the development of our next-generation AI drug design engine, help us advance our own programs into clinical development, and is a significant step forward towards our mission of one day solving all disease with the help of AI.
Demis Hassabis, Founder & CEO
At Thrive, we aim to invest in category-defining companies with singular conviction, and that has led us to Isomorphic Labs. We believe Isomorphic has earned a rare position to define a new age of drug discovery and design, and we are deeply inspired by their mission and the extraordinary progress they have made to date.
Joshua Kushner, Founder at Thrive Capital
AI and machine learning have long held the promise of transforming drug discovery, yet few companies over the past decade have unlocked their full potential. After witnessing the extraordinary pace of innovation at Isomorphic Labs, we believe their pioneering approach will redefine AI-powered drug discovery. With Sir Demis Hassabis at the helm, Isomorphic has assembled an exceptional team at the intersection of life sciences and technology. We're proud to support them as they advance the development of new treatments for patients.
Dr. Krishna Yeshwant, Managing Partner at GV
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